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pentobarbital will minimize the level or outcome of netupitant/palonosetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Netupitant is mainly metabolized by CYP3A4; stay clear of use in patients who will be chronically applying a solid CYP3A4 inducerYet whether or not the bill experienced handed in New So